The Tissue-Tek® Cryo3® Flex Cryostat is the 3rd generation of the established, reliable and trusted Cryo3 platform for fast sectioning of frozen tissue specimens. It was designed to decrease the time to get complete sections, and in parallel to preserve valuable tissue.
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The Tissue-Tek® Cryo3® Flex Cryostat produces superior sections from 1 to 99 µm using a temperature-controlled blade holder and a 3D Precision Chuck to accurately align the block face to the blade, reducing operator’s trimming time and preserving specimens. The sturdy chuck retains its position when locked and unlocked, eliminating any time and effort spent realigning the cutting angle.
Users can now leverage the newly developed Anti-Roll Rake that was designed to best mimic the preferred and widely accepted "Brush Technique" to prevent sections from rolling, which in addition, reduces the learning curve of new users making them proficient faster.
For the first time in the history of cryotomy, Sakura successfully integrated its advanced remote diagnostics technology platform, iSupport, into the hardware and software of the Cryo3 Flex. The plug-and-play connection opens communication to a secure remote service that ensures maximum uptime through fast reaction to instrument alerts by Sakura’s professional technical support team.
A color touch LCD screen provides a visual display of critical sectioning information such as current chamber temperature, section thickness, and trimming thickness. The Cryobar® offers 12 positions, allowing operators to use the Cryomold® method or direct method at the same time. The Cryo+™ area of the Cryobar freezes to -50◦ C, within 5 minutes after activation.
The motorized advance and retract keys allows smooth, precise orientation of the 3D Precision Chuck to the blade holder. The blade holder accommodates Accu-Edge high and low-profile disposable blades.
The Tissue-Tek Cryo3 Flex D and DM models offer innovative options like motorized sectioning, ozone disinfection, and a vacuum debris removal system. The Cryo3 Flex now uses a more efficient and patented ozone technology to safely protect operators from pathogens in between weekly decontamination requested by CAP Accreditation Guidelines. The combination of ozone, UV and elevated temperatures provide unprecedented disinfection with a reduction of up to 5 logs for the SV40 virus.
|3D Precision Chuck
- Obtain complete sections faster
- Retains position when locked and unlocked
- Quick and precise fine angle adjustments on all 3 axes (XYZ)
|1" Travel Distance
|Utility Tray with Storage Space
- Store up to 32 specimen holders in the chamber to keep as many blocks frozen for immediate recuts
|2 Optional Ergonomic Handles
- Section more comfortability
- Help prevent Repetitive Motion Disorder (RMD)
|iSupport: Online Report Diagnostics Technology
- Maximze instrument uptime
- Get instrument support faster
(D and DM models)
- Protect yourself from pathogens with an unprecedented disinfection of up to 5 logs for the SV40 virus
- Prevent sections from rolling
||(#6200) Tissue-Tek® Cryo3® Flex Cryostat, Basic
(#6201) Tissue-Tek® Cryo3® Flex Cryostat, D
(#6202) Tissue-Tek® Cryo3® Flex Cryostat, DM
||25.8 x 29.7 x 47.0 inches
(65.4 x 75.4 x 119.4 cm)
||373 lbs (169.2 kg)
||115/120 VAC, 50/60 Hz, 11 Amps
The instrument must be connected to an electrical outlet which supplies the proper voltage (within ± 10%)
||USB and LAN
Set Point Range:
|-35°C to 0°C; Chamber temperature is maintained within ±2°C
||When activated Cryo+ is 20°C lower than the Chamber temperature, within 5 minutes. Lowest Cryo+ temperature is -50°C
|Section Thickness Settings:
||1 to 99 μm in 1 μm steps
|Maximum Specimen Thickness:
||1 to 100 μm in 1 μm steps
|Specimen Holder Sizes:
||Round 26 mm, 36 mm, 55 mm
(all including an alignment mark on the shaft)
||±8° (XY axis), 360° (Z axis)
||3D Precision Chuck secures the Specimen Holder to the Microtome. Dial indicators show the exact angle of the Chuck. The guide marks show the exact orientation of the Specimen Holders in the Chuck
||Vertical: 2.5 inches (63.0 mm)
Horizontal: 1.0 inch (25.4 mm)
||Manual start: Defrosts the Chamber within 30 minutes, when activated
Automatic start: Defrosts the Chamber within 1 hour; start time can be set within a 24 hour period
|Disinfection (D and DM only):
||Manual start: Two Ozone Disinfections cycles are available:
• Long: approximately 135 minutes (warm)
• Short: approximately 45 minutes (cold)
Automatic start: always performs a Long Disinfection Cycle.
Start time can be set within a 24 hour period
Tissue-Tek® Cryo3® Flex Cryostat 3D Precision Chuck
Tissue-Tek® Cryo3® Flex Cryostat Anti-Roll Rake
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